Sex plays an important role in the creation of wholesome, fulfilling partnerships.  Sex is a healthy activity because it has similar benefits to physical exercise and the release of "pleasure-inducing endorphins in the brain" is good for mental health as well.  Furthermore, sex "creates an emotional and physical bond that is essential for social support". To achieve the highest levels of healthy sexual fulfillment, a man should learn ways to delay ejaculation and thus heighten the orgasmic experience for both himself and his partner.  It is also important to note that the healthiest sex connections are those that involve feelings of love. In addition, in order to maintain a healthy sexual relationship, a man needs to overcome the stereotypes of masculinity. For example, men are conditioned to be competitive, dominant, aggressive, and demanding. However, it is widely agreed that "these attitudes don't lead to satisfying relationships". In order for a healthy sex connection to exist between partners, there is a need for trust, honesty, respect and equality on both sides. Even though men and women are quite different from one another in terms of their bodies, emotions, minds, and social conditioning, it is nonetheless possible for them to communicate and to find a middle ground where they both feel comfortable. Homosexual relationships also require open communication and feelings of trust.

In order for a sexual relationship to be healthy, it is important to take the necessary precautions to prevent the spread of sexually transmitted diseases (STD's). Such diseases include pubic lice, herpes, gonorrhea, syphilis, and HIV (which can be a precursor of the life-threatening illness known as AIDS).  The Planned Parenthood Federation recommends that sexual partners make use of the practices of "safer sex." For example, the risks will be reduced if both partners are monogamous and able to fully trust each other. Partners who do not know each other well should be sure to use a condom when engaging in sex.  Another way to have "safer sex" is to focus on sexual play and exploration rather than intercourse. Some people are concerned that the time and effort involved in having "safer sex" will diminish the pleasure of the experience. In actuality, however, this approach can increase satisfaction for both partner while contributing to feelings of intimacy and trust, and improving the ability to communicate.